Amphetamines

Amphetamines be part of a class of drugs called stimulants that affect the sound nervous system. It is also known as 1-methyl-2-phenethylamine, 1-phenyl-2-aminopropane, and Benzedrine. It is made up of a 50/50 mixture of the l and d isomers. The l isomer affects the body, and the d isomer affects the brain. It boils at 200ºC and is dissolvable in alcohol and ether, slightly soluble in water. It was chancellor created in Germany in 1887. In the 1930s and 40s amphetamine was handling in the treatment of asthma, depression, obesity, and narcolepsy. Amphetamines chemical structure is very resembling to the neurotransmitter Adrenaline. chemical substance structure of Amphetamine, C H CH CH(NH ) CH Method of Preparation on that point are many ways of creating amphetamines. unity way is to seduce two mols, for example, 270 grams, of racemic amphetamine base to play off with unrivaled mol (150 grams) of d-tartaric hot, forming a dl-amphetamine d-tartrate, or a unb iased salt. The objective salt obtained is dissolved by the addition of nearly 1 litre, of ethanol, and heating to boiling point. The solution then must(prenominal) be cooled to way temperature with occasional stirring to effect crystallisation. The crystals are filtered out and willing be found to contain laevo enantiomorph, which is the left wing of a pair of crystals that are a mirror regard of from each one other.

It is then recrystallised and the predominance of the l-enantiomorph is found to be change magnitude and the process is repeated until no further change is polish off and a concentration of 8 grams per 100 cc of aqueous solution is obtained. Finally the product ob tained is l-amphetamine d-tartrate. d-amphet! amine may be remember from this by the addition of tartaric pane for the formation of acid tartrates and separation of d-amphetamine d-bitartrate by crystallisation. Properties and Chemical Reactions of Amphetamines Amphetamines vary... If you want to get a full essay, order it on our website: OrderEssay.net

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